TABLE 1

Demographic and baseline characteristics

ParameterValue(s) for cohort:
1a (n = 30)2b (n = 9)3c (n = 13)4d (n = 14)5e (n = 14)All subjects (n = 80)
Age, yr
    Mean (SD)24.7 (4.3)27.9 (7.5)28.2 (8.0)27.6 (9.6)25.8 (7.3)26.3 (6.9)
    Median (range)25.0 (18–38)27.0 (21–44)25.0 (22–50)24.5 (19–50)22.5 (19–42)25.9 (18–50)
Sex, n (%)
    Male21 (70.0)9 (100.0)8 (61.5)9 (64.3)10 (71.4)57 (71.3)
    Female9 (30.0)05 (38.5)5 (35.7)4 (28.6)23 (28.8)
Race, n (%)
    White29 (96.7)9 (100.0)11 (84.6)14 (100.0)13 (92.9)76 (95.)
    Pacific Islander001 (7.7)001 (1.3)
    Asian1 (3.3)01 (7.7)01 (7.1)3 (3.8)
BMI (kg/m2), mean (SD)24.7 (2.3)24.2 (2.7)24.5 (2.4)23.1 (1.4)23.6 (2.7)24.1 (2.4)
  • a Meropenem, 1,000 mg; vaborbactam, 250 mg.

  • b Meropenem, 1,000 mg; vaborbactam, 1,000 mg.

  • c Meropenem, 1,000 mg; vaborbactam, 1,500 mg.

  • d Meropenem, 1,000 mg; vaborbactam, 2,000 mg.

  • e Meropenem, 2,000 mg; vaborbactam, 2,000 mg.