TABLE 2

Demographics of obese and nonobese adult subjectsa

CharacteristicValue for the following subjects:
Normal to overweight (n = 8)Obese class I (n = 8)Obese class II (n = 8)Obese class III (n = 8)
Mean ± SD age (yr)30.8 ± 8.229.8 ± 9.028.5 ± 6.136.3 ± 8.5
No. (%) of male subjects4 (50)6 (75)6 (75)4 (50)
No. (%) of subjects of the following race/ethnicity:
    Black2 (25)3 (37.5)3 (37.5)4 (50)
    White, Hispanic1 (12.5)2 (25)2 (25)1 (12.5)
    White, non-Hispanic3 (37.5)2 (25)2 (25)1 (12.5)
    Other2 (25)1 (12.5)1 (12.5)2 (25)
Mean ± SD total body wt (kg)72.2 ± 12.2102.4 ± 8.9110.0 ± 5.9140.2 ± 9.8
Mean ± SD adjusted body wt (kg)67.9 ± 7.682.9 ± 7.984.3 ± 6.296.6 ± 5.6
Mean ± SD ht (in.)67.6 ± 1.868.9 ± 2.867.9 ± 2.468.2 ± 1.6
Mean ± SD BMI (kg/m2)24.4 ± 3.333.2 ± 1.436.8 ± 1.446.2 ± 2.5
Mean ± SD eCLCR (ml/min)91.5 ± 20.598.2 ± 18.297.7 ± 14.790.5 ± 7.9
Mean ± SD mCLCR (ml/min)127.5 ± 16.2175.9 ± 37.3165.2 ± 36.0151.1. ± 28.2
  • a Abbreviations: BMI, body mass index; eCLCR, estimated creatinine clearance calculated using the Cockcroft-Gault equation (42) and ideal body weight (40); mCLCR, measured creatinine clearance determined from a 24-h urine creatinine collection.