TABLE 1

EC50 values for aminoglycoside combinationsa

AntibioticAdjuvantEC50 (μM)95% confidence interval (μM)
TobramycinTriclosan20.507.65–83.78
GentamicinTriclosan23.0612.08–44.02
StreptomycinTriclosan28.9624.45–34.31
  • a EC50 values were calculated using Prism version 5. Log10 (inhibitor) versus response–variable slope (four parameters) analyses were performed. EC50 values for aminoglycoside alone were not constructed, because no curve was established due to their ineffectiveness against biofilms.