TABLE 1

IC50 values and selectivity indexes for the effect of K22 treatment on flavivirus infectivity

Virus24 h p.i.48 h p.i.
IC50 (μM)SIaIC50 (μM)SI
ZIKV2.535.62.139.9
JEV0.5193.94.419.1
YFV3.724.32.336.7
WNV2.832.38.410.0
USUV9.010.0∼10.0∼8.4
WESSV5.915.26.812.5
  • a SI, selectivity index.