TABLE 1

MICs of antifungal agents for S. pombe prohibitin overexpression strains

StrainaMICb
CLTFLZTRBAMB5-FUCASPG
wt + vector0.060160.000.060.5062.504.004.00
wt + phb2+0.12320.000.121.0062.504.008.00
wt + phb1+0.060160.000.060.5062.504.004.00
  • a wt, wild type.

  • b Expressed in micrograms per milliliter for clotrimazole (CLT), fluconazole (FLZ), terbinafine (TRB), amphotericin B (AMB), 5-fluorouracil (5-FU), and caspofungin (CAS) and in millimolar concentrations for phenylglyoxal (PG).