TABLE 2

Relative within-host and transmission fitness between viral pairs tested in competitive mixtures during ferret infection

MutantCorresponding wild typeRelative within-host fitness (R0 ratio [95% CI])aRelative transmission fitness (95% CI)b
Mut-Y273WT-H2730.84 (0.70, 1.02)0.90 (0.60, 1.35)
Mut-N197WT-D1970.94 (0.81, 1.10)2.78 (1.56, 5.53)
  • a If the R0 ratio is <1, it indicates fitness advantage of wild type over the mutant, and if the R0 ratio is >1, the mutant is fitter than the wild type.

  • b Relative transmission fitness value of <1 indicates fitness advantage of the wild type over mutant, and a fitness value of >1 indicates that the mutant is fitter than the wild type.