TABLE 2

IC50 values, CC50 values, and selectivity indexes for the effect of K22 treatment on hepacivirus and pestivirus replication and infectivity

VirusIC50 (μM) for:SIaCC50 (μM) for:
ReplicationInfectivityProliferationCytotoxicity
HCV7.02.29.721.3
BVDV SuwaCp15.514.2>24.6>350>1,000
BVDV SuwaNcp34.721.4>16.4>350>1,000
  • a SI, selectivity index.