TABLE 2

Treatment options for OXA-48 producers

Drug regimenReference(s)No. of patientsType of infection (n)Microbiological cure (%)Survival at 14–30 d (%)
Ceftriaxone27, 592Endometritis (1)a100
Bloodstream infection (1)
Carbapenem4, 272910Pneumonia (1)0–66
Bloodstream infection (9)
Amikacin273Bloodstream infection (3)66
Colistin271Bloodstream infection (1)100
Tigecycline272Bloodstream infection (2)100
Ceftazidime-avibactam60, 6118Bloodstream infection (5)2522.7–70.6
Ceftazidime plus colistin581Catheter-related bloodstream infection (1)100
Carbapenem plus amikacin27, 664Bloodstream infection (4)66–100
Carbapenem plus colistin4, 27, 29, 657Catheter-related bloodstream infection (1)0–100
Bloodstream infection (4)
Pneumonia (1)
Intraabdominal infection (1)
Colistin plus fosfomycin274Bloodstream infection (4)75
Colistin plus amikacin271Bloodstream infection (1)100
Tigecycline plus amikacin274Bloodstream infection (4)50
Tigecycline plus fosfomycin271Bloodstream infection (1)100
Tigecycline plus colistin276Bloodstream infection (6)83
Carbapenem plus amikacin plus colistin42Catheter-related bloodstream infection (1)50
Pneumonia (1)
Colistin plus amikacin plus tigecycline272Bloodstream infection (2)50
  • a —, data not available.