TABLE 1

In vitro antifungal susceptibility of 189 clinical and environmental isolates of A. flavus to azoles

DrugSourceSusceptibilitya
RangeMIC50MIC90GMECV% ≤ECV
ItraconazoleClinical0.03–16.00.120.50.14198.3
Environmental0.03–0.1250.060.1250.06100
VoriconazoleClinical0.03–8.00.51.00.43195.04
Environmental0.15–1.00.51.00.50100
PosaconazoleClinical0.015–0.50.060.250.050.2598.95
Environmental0.015–0.060.030.030.022100
  • a All values are in μg/ml. GM, geometric mean; ECV, epidemiological cut off value (34).