TABLE 2

Pharmacokinetic parameters of ETX2514 and sulbactam in plasma following the third i.v. dose of ETX2514SULa

DrugCmax (mg/liter)Cmin (mg/liter)AUC0–6 (mg · h/liter)t½ (h)Vss (liters)CL (liters/h)
ETX251433.41 ± 8.995.79 ± 2.08109.05 ± 23.441.40 ± 0.1816.7 ± 3.09.56 ± 1.92
Sulbactam23.10 ± 7.612.50 ± 1.0967.89 ± 16.691.12 ± 0.1420.7 ± 4.315.56 ± 3.63
  • a Data (means ± SDs) from 30 subjects per parameter estimate.