TABLE 3

B. burgdorferi N40 cultures from ear punches during antibiotic treatment in wild-type and SCID mouse infection modelsa

Mouse groupTreatment groupNo. with positive ear punch culture
Day 1Day 2Day 3Day 4
WTSaline5445
Doxycycline1000
Ceftriaxone0000
Vancomycin0000
SCIDSaline6446
Doxycycline6544
Ceftriaxone0000
Vancomycin0000
  • a The following doses were given every 12 h for 5 days: doxycycline, 50 mg/kg; ceftriaxone, 156 mg/kg; and vancomycin, 110 mg/kg. n = 6 per treatment group.