Parameter^{a} | Mean | Median | Standard deviation |
---|---|---|---|

V (liters) | 338.8 | 351.3 | 22.44 |

CL (liter/h) | 19.63 | 19.75 | 0.0506 |

K_{g} (h^{−1}) | 0.0350 | 0.0204 | 0.0279 |

K_{kill} (h^{−1}) | 0.677 | 0.301 | 0.430 |

C_{50} (mg/liter) | 4.87 | 4.97 | 0.237 |

H^{b} | 4.65 | 4.39 | 0.436 |

POPMAX (CFU/ml) | 1.00 × 10^{7} | 1.04 × 10^{7} | 2.92 × 10^{3} |

K_{nat-death} (h^{−1}) | 0.0439 | 0.0321 | 0.0225 |

IC_{2} (CFU/ml) | 3.00 × 10^{5} | 3.01 × 10^{5} | 4.68 |

↵a

*V*, volume of distribution; CL, clearance;*K*_{g}, first-order growth rate constant;*K*_{kill}, first-order kill rate constant;*C*_{50}, moxifloxacin concentration at which the kill rate is half-maximal;*H*, Hill constant; POPMAX, maximal bacterial concentration;*K*_{nat-death}, first-order kill rate constant independent of moxifloxacin concentration; IC_{2}, initial condition of*M. tuberculosis*concentration.↵b Unitless.