TABLE 1

Activity of sarecycline and comparator agents against 55 clinical isolates of C. acnes

AgentMIC (µg/ml)
Range50%90%
Sarecycline0.5 to 160.54
Tetracycline0.5 to 3212
Doxycycline0.25 to 160.52
Minocycline0.12 to 80.251
Clindamycin≤0.06 to 64≤0.064
Erythromycin≤0.06 to >128≤0.06>128