TABLE 3

LDM LBP residues within 4 Å of PCZa

SRS no. or groupScLDM6×His + PCZN-truncCaLDM6×His + PCZ
SRS1A124AYAHLTTPVFGKGVIYDCP143E116AYKHLTTPVFGKGVIYDCP135
SRS4I304ANLLIGVLMGGQHTSAA321I297ANLLIGILMGGQHTSAS314
SRS5H378PLHSLFR385M374PLHSIFR381
SRS6D505FTSMVTLPTG515D504YSSMVVLPTE514
Helix A′A69V70, Y72GM74A61, Y64GQ66
Helix FF′F236, P238, F241F228, P230, F233
Additional residues
in LBP surface
V66 L95L96, R98, M100, L147, Q150K151,
V154, I239, V242, H405, I471
F58, P68, L87L88, K90, M92, L139, Q142K143,
A146, I231, V234, Y401, I471
  • a Amino acid residues in the LBP are shown in italics, and residues within 4 Å of PCZ are in bold.