TABLE 1

Activities of DAQ compounds

H37Rv strainIC90 (μM)a
IDR-0010006IDR-0258237
Wild type15 ± 222 ± 3
Rv3161cC115W mutant38 ± 659 ± 8
  • a IC90 was determined in liquid medium and is defined as the concentration required to inhibit growth by 90%. The results are the average ± standard deviation from a minimum of 2 experiments.