TABLE 1

Overview of study groups and detection of bacteria postmortem

GroupAnimal no.InoculumDetection of bacteria in implant cavity (swab)Detection of biofilm in:
Implant (sonication)Tissue around implant cavity (IHCa)
AA1SalineNoNo
A2SalineNoNo
A3SalineNoNo
A4SalineNoNoNo
A5SalineNoNoNo
A6SalineNoNoNo
BB1S. aureusYes (inoculated spa type)YesYes
B2S. aureusYes (inoculated spa type)YesNo
B3S. aureusYes (inoculated spa type)YesYes
B4S. aureusYes (inoculated spa type)YesYes
B5S. aureusYes (inoculated spa type)YesYes
B6S. aureusYes (inoculated spa type)YesYes
CC1S. aureus + 160× MIC (40 mg/liter)Yes (inoculated spa type)YesYes
C2S. aureus + 160× MICYes (inoculated spa type)YesNo
C3S. aureus + 160× MICYes (inoculated spa type)YesYes
DD1S. aureus + 1,600× MIC (400 mg/liter)ContaminationYesNo
D2S. aureus + 1,600× MICYes (inoculated spa type)YesNo
D3S. aureus + 1,600× MICYes (inoculated spa type)NoNo
EE1S. aureus + 16,000× MIC (4,000 mg/liter)NoYesYes
E2S. aureus + 16,000× MICNoNoNo
E3S. aureus + 16,000× MICYes (inoculated spa type)YesNo
FF1S. aureus + 160,000× MIC (40,000 mg/liter)NoNoNo
F2S. aureus + 160,000× MICYes (inoculated spa type)YesNo
F3S. aureus + 160,000× MICNoNoNo
F4S. aureus + 160,000× MICNoNoNo
  • a IHC, immunohistochemistry for S. aureus.