TABLE 1

WNV inhibition and cytotoxicity characteristics of the studied nucleoside analogues in PS cells

  • aDetermined from three independent experiments.

  • bExpressed as a 50% reduction of viral titers and calculated as inflection points of sigmoidal inhibitory curves, which were obtained by a nonlinear fit of transformed inhibitor concentrations versus normalized response using GraphPad Prism 7.04 (GraphPad Software, Inc., USA).

  • cSI = CC50/EC50.

  • dND, not determined.

  • eValues reported previously by Eyer et al. (27).