TABLE 1

Physical characteristics of nanoparticle formulationsa

FormulationMean particle size (nm) ± SDMean ZP (mV) ± SDPDIMean LC% ± SDMean EE% ± SD
NPs227.1 ± 5.06−1.84 ± 0.250.223
AmB-NPs287.8 ± 8.64−10.9 ± 1.90.2055.7 ± 0.1285 ± 2.4
  • a NPs, plain PLGA nanoparticles; AmB-NPs, amphotericin B-loaded PLGA nanoparticles; ZP, zeta potential; PDI, polydispersity index; LC, loading content; EE, entrapment efficiency.