TABLE 1

Contribution of different resistance determinants from A. nosocomialis and A. pittii to carbapenem resistance in A. baumannii

StrainaOriginal strainMIC (μg/ml)b
ImipenemMeropenem
2010N07-10010.5
2010N07-100 (pAB-NCGM253-like with blaOXA-72)2014E03-147>16>16
2010N07-100 (plasmid with IS1006-ΔISAba3-blaOXA-58)2010S01-197>16>16
2010N07-100 (plasmid with IS15DI-ΔISAba3-blaOXA-58)2014N23-120>16>16
ATCC 17978 (pYMAb2)≤0.25≤0.25
ATCC 17978 (pYMAb2::blaOXA-500)c2014S07-126≤0.25≤0.25
  • a A carbapenem-susceptible A. baumannii clinical isolate (2010N07-100) was the recipient.

  • b The MICs were determined using the broth microdilution method.

  • c blaOXA-500 belongs to the blaOXA-272-like branch of blaOXA-213-like in A. pittii.