MIC range, geometric mean, MIC mode, MIC50, and MIC90 of diacerein and its metabolite rhein against 65 common clinical ocular Gram-positive bacterial isolates

Antibacterial agent by bacterial species (n)MIC (μg/ml)a
Staphylococcus epidermidis (38)
Staphylococcus aureus (7)
Staphylococcus intermedius (6)
Enterococcus spp. (3)
Streptococcus sanguinis (8)
Streptococcus pneumoniae (3)
  • a All MICs were determined visually; the MIC50 and MIC90 values represent the concentrations required to inhibit 50% and 90% of the tested strains. GM, geometric mean.

  • b P < 0.05 compared with levofloxacin.

  • c P < 0.05 compared with amikacin; analyzed using one-way ANOVA.