TABLE 10

PD50s for cefepime, cefepime-AAI101, and meropenem against tested isolates

Clinical isolatePD50 (mg/kg)
CefepimeCefepime-AAI101 (2:1, wt/wt)aMeropenem
E. coli ATCC 259220.050.060.23
K. pneumoniae R-43>30015.103.82
K. pneumoniae B-124141.0012.7743.05
E. cloacae B-143>30015.9720.26
  • a The PD50 value for cefepime-AAI101 represents the cefepime component.