TABLE 2

Child-Pugh score, SOFA score, vital organ support, and parameters of hepatic and renal functiona

ParameterValue(s) on day:
2 (n = 46)5 (n = 37)
Child-Pugh, n (%)
    Score 52 (4)2 (5)
    Score 63 (7)0
    Score 725 (54)24 (65)
    Score 83 (7)6 (16)
    Score 912 (26)5 (14)
    Score 101 (2)0
    Class A5 (11)2 (5)
    Class B40 (87)35 (95)
    Class C1 (2)0
SOFA score, median (range)9 (2–21)7 (2–17)
Vital organ support, n (%)
    CRRT21 (45)15 (40)
    Ventilator41 (89)30 (81)
    ECMO9 (20)9 (20)
Parameters of hepatic and
renal function, median (range)
    P-bilirubin, μmol/liter24 (4–286)18 (4–296)
    P-albumin, g/liter18.5 (11–44)20 (12–39)
    P-INR1.2 (0.9–1.8)1.2 (1.0–1.7)
    P-ALT, μkat/liter0.64 (0.15–10.5)0.86 (0.15–8.0)
    P-ALP, μkat/liter1.7 (0.59–8.6)1.8 (0.9–8.0)
    P-creatinine, μmol/liter97 (29–550)96 (36–289)
    GFR, ml/min/1.73m²84b (23–116)89c (25–117)
  • a Values are given in absolute numbers (percent) or median (range). SOFA score, sequential organ failure assessment score; CRRT, continuous renal replacement therapy mainly performed as continuous venovenous hemodialysis; ECMO, extracorporeal membrane oxygenation; P, plasma; INR, international normalized ratio; ALT, alanine aminotransferase; ALP, alkaline phosphatase; μkat/liter, microkatal/liter; GFR, glomerular filtration rate as estimated by the Modification of Diet in Renal Disease Study equation.

  • b Twenty-five patients (patients with CRRT excluded).

  • c Twenty-two patients (patients with CRRT excluded).