TABLE 1

Ranges of antifungal susceptibilities, geometric means, and MIC50s of the species studied

Group (no. of isolates)MIC (mg/liter)a
AMBNATTRBISAITCPOS
C. recurvatus (3)
    GMb0.032.040.35.03.23.2
    MIC50NAcNANANANANA
    Range≤0.03216–322–80.125–80.125–8
M. amphibiorum (3)
    GM0.031.620.216.00.10.04
    MIC50NANANANANANA
    Range≤0.031–28–32>80.06–0.50.016–0.125
M. ardhlaengiktus (2)
    GM0.042.86416.016.016.0
    MIC50NANANANANANA
    Range≤0.03–0.062–4>32>8>8>8
M. circinelloides (14)
    GM0.11.9645.13.10.6
    MIC500.1252>32440.5
    Range≤0.03–0.51–4>322–80.5–80.125–4
M. griseocyanus (4)
    GM0.12.0646.72.80.6
    MIC50NANANANANANA
    Range≤0.03–0.52>324–82–40.25–1
M. indicus (10)
    GM0.042.56416.013.02.8
    MIC500.032>32>881
    Range≤0.03–0.1252–4>32>82–80.25–8
M. irregularis (7)
    GM0.031.86410.84.00.3
    MIC50NANANANANANA
    Range≤0.031–2>324–80.5–80.125–2
M. janssenii (5)
    GM0.081.5643.01.50.3
    MIC50NANANA420.125
    Range≤0.03–0.51–4>322–40.5–40.06–0.5
M. lusitanicus (13)
    GM0.082.56413.612.39.4
    MIC500.062>32>888
    Range≤0.03–0.251–4>324–82–81–8
M. racemosus (4)
    GM0.062.02.80.30.60.1
    MIC50NANANANANANA
    Range≤0.03–0.51–40.06–32≤0.016–20.016–20.016–0.5
M. ramosissimus (1)
    GM
    MIC50
    Range0.061>32>8>8>8
M. variicolumellatus (2)
    GM0.031.4645.70.70.7
    MIC50NANANANANANA
    Range≤0.031–2>324–80.5–10.5–1
M. velutinosus (7)
    GM0.042.2642.41.10.3
    MIC50NANANANANANA
    Range≤0.03–0.1252–4>322–40.5–40.125–2
Mucoraceae
    GM0.062.0251.096.593.570.98
    MIC500.032>32820.5
    Range≤0.03–0.51–20.06–32≤0.016–80.016–80.016–8
R. arrhizus (6)
    GM0.24.557.01.11.80.3
    MIC50NANANANANANA
    Range≤0.03–22–832–320.5–40.5–80.125–1
R. microsporus (6)
    GM0.62.60.11.72.20.5
    MIC50NANANANANANA
    Range0.25–12–4≤0.06–0.51–41–80.125–2
Rhizopus spp.
    GM0,413.52.641.3720.37
    MIC500.540.5110.5
    Range≤0.03–22–8≤0.06–320.5–40.5–80.125–2
L. ramosa (2)
    GM0.032.00.182.80.70.06
    MIC50NANANANANANA
    Range≤0.0320.125–0.252–40.25–20.03–0.125
L. corymbifera (8)
    GM0.112.80.091.80.50.1
    MIC50NANANANANANA
    Range≤0.03–0.52–4≤0.06–0.250.5–40.25–20.06–0.5
Lichtheimia spp.
    GM0.092.640.1020.570,12
    MIC500.12520.0620.50.125
    Range≤0.03–0.52–4≤0.06–0.250.5–40.25–20.03–0.5
R. pusillus (4)
    GM0.072.50.12.80.20.1
    MIC50NANANANANANA
    Range≤0.03–0.252–4≤0.06–10.25–80.125–80.03–1
Lichtheimiaceae
    GM0.072,560.112.10,530,11
    MIC500.0620.0620.50.125
    Range≤0.03–0.52–4≤0.06–10.25–80.125–80.03–1
  • a AMB, amphotericin B; NAT, natamycin; TRB, terbinafine; ISA, isavuconazole; ITC, itraconazole; POS, posaconazole.

  • b GM, geometric mean.

  • c NA, not applicable.