TABLE 1

Baseline patient characteristics

Patient characteristicbNormal renal function (n = 8)RIESRD (n = 6)
Mild (n = 6)Moderate (n = 6)Severe (n = 8)
Age (yrs)a59.6 ± 7.664.5 ± 5.862.3 ± 8.559.9 ± 11.051.2 ± 9.7
Male (n [%])5 (62.5)3 (50.0)2 (33.3)5 (62.5)3 (50.0)
Race (n [%])
    White7 (87.5)3 (50.0)5 (83.3)6 (75.0)2 (33.3)
    Black or African American1 (12.5)3 (50.0)1 (16.7)2 (25.0)4 (66.7)
Hispanic or Latino (n [%])4 (50.0)004 (50.0)1 (16.7)
Wt (kg)a83.6 ± 9.783.2 ± 15.393.6 ± 18.783.9 ± 8.488.5 ± 19.5
BMI (kg/m2)a28.6 ± 2.830.7 ± 5.631.9 ± 5.630.4 ± 4.430.0 ± 5.7
eGFR (ml/min/1.73 m2)a92.0 ± 11.071.8 ± 15.542.0 ± 9.014.9 ± 6.57.7 ± 3.0
CLCR (ml/min)a111.2 ± 19.779.3 ± 13.861.6 ± 12.822.4 ± 9.913.3 ± 4.9
  • a Mean ± standard deviation.

  • b BMI, body mass index; CLCR, creatinine clearance; eGFR, estimated glomerular filtration rate.