TABLE 5

Kd(app) of CorA with metal cations and compound 10

CorA additive in fluorescence shift assayKd(app) (μM)
Mg2+47.5 ± 3.0
Co2+205 ± 18
Compound 1020.0 ± 4.3
Compound 10/1 mM Mg2+24.1 ± 6.3
Compound 10/1 mM Co2+21.8 ± 4.1