TABLE 3.

IC50s of clavulanic acid and tazobactam for β-lactamases GES-14, GES-1, and GES-2a

InhibitorIC50 (μM) for:
GES-14GES-1bGES-2b
Clavulanic acid151
Tazobactam0.152.50.5
  • a Data are the means of three independent experiments. Standard deviations were within 10% of the means.

  • b Data for GES-1 and GES-2 IC50s are from references 22 and 23, respectively.