Table 1.

In vitro susceptibilities of Aspergillus spp. to E1210 and comparators as determined by CLSI and EUCAST broth microdilution methods

Species (no. tested)Antifungal agentTest methodNo. of isolates at indicated MIC/MEC (μg/ml)% EAa
≤0.0080.0150.030.060.120.250.5124≥8
A. flavus SC b (20)E1210EUCAST4142100.0
CLSI11441
AnidulafunginEUCAST191100.0
CLSI20
CaspofunginEUCAST416100.0
CLSI1154
ItraconazoleEUCAST713100.0
CLSI713
PosaconazoleEUCAST2171100.0
CLSI1163
VoriconazoleEUCAST1127100.0
CLSI41411
A. fumigatus SC (22)E1210EUCAST5134100.0
CLSI11164
AnidulafunginEUCAST175100.0
CLSI148
CaspofunginEUCAST3154100.0
CLSI4171
ItraconazoleEUCAST2137100.0
CLSI11416
PosaconazoleEUCAST131251100.0
CLSI8761
VoriconazoleEUCAST112441100.0
CLSI410341
A. niger SC (13)E1210EUCAST562100.0
CLSI85
AnidulafunginEUCAST13100.0
CLSI121
CaspofunginEUCAST13100.0
CLSI49
ItraconazoleEUCAST1363100.0
CLSI652
PosaconazoleEUCAST247100.0
CLSI184
VoriconazoleEUCAST454100.0
CLSI454
A. terreus SC (23)E1210EUCAST2174100.0
CLSI11183
AnidulafunginEUCAST203100.0
CLSI158
CaspofunginEUCAST1184100.0
CLSI212
ItraconazoleEUCAST1571100.0
CLSI11561
PosaconazoleEUCAST1147191.3
CLSI71411
VoriconazoleEUCAST11111100.0
CLSI41351
  • a EA, essential agreement.

  • b SC, species complex.