Table 1.

Genetic features associated with the blaNDM-1 gene

StrainCountry of isolationCountry of originST typePlasmid type carrying blaNDM-1Size (kb)Associated resistance determinantsaISAba125bleMBLReferenced
E. coli 271AustraliaBangladeshST101Untypeableb35CTX-M-15, TEM-1 ArmA, RmtB, QepATruncated+19
E. coli GUEFranceIndiaST131IncF110TEM-1, OXA-1++18
E. coli RICFranceIndiaST10IncA/C150CMY-16, TEM-1, OXA-1, OXA-10+This study
E. coli I5IndiaIndiaST648IncF70CTX-M-15, CMY-6, ArmA++This study
E. coli RKIGermanyIndiaST101ChromosomeCTX-M-15, TEM-1, OXA-1, OXA-2, RmtC, AAC(6′)-Ib-cr++15
E. coli 5649SwitzerlandSerbiaST410IncF130CMY-30, TEM-1, OXA-1, ArmA++22
K. pneumoniae K2IndiaIndiaST14Untypeable150CTX-M-15, TEM-1, SHV-28, OXA-1, OXA-9, CMY-6, RmtC, AAC(6′)-Ib++This study
K. pneumoniae 6642SwitzerlandIndiaST147IncA/C150CTX-M-15, TEM-1, SHV-28, OXA-1 RmtA, QnrB1+22
K. pneumoniae 6759SwitzerlandSerbiaST25IncA/C150CTX-M-15, TEM-1, SHV-11, OXA-1, OXA-9, OXA-10, CMY-16, QnrA6+22
K. pneumoniae IBNIraqIraqST147Untypeable100CTX-M-15, SHV-11, OXA-1, QnrA1++17
K. pneumoniae Kp7KenyaKenyaST14IncA/C120CTX-M-15, TEM-1, SHV-28, OXA-1, OXA-9, CMY-6, RmtCTruncated+20
K. pneumoniae 601OmanOmanST14IncL/M170CTX-M-15, TEM-1, SHV-11, SHV-28, OXA-1, OXA-9, ArmATruncated+16
K. pneumoniae 419OmanIndiaST340Untypeable170SHV-11, OXA-1, ArmA, QnrB1++16
C. freundii STEFranceIndiaNDcUntypeable65CTX-M-15, TEM-1, OXA-1, OXA-9, OXA-10, OXA-181, VIM-4, ArmA, QnrB30++21
P. mirabilis 7892SwitzerlandPakistanNDIncA/C150TEM-1, OXA-1, OXA-10, CMY-16, ArmA+22
P. stuartii PS1IndiaIndiaNDChromosomeTEM-1, OXA-1, CMY-6, RmtC++This study
  • a Resistance markers being coharbored by the blaNDM-1 plasmid are in bold type.

  • b Untypeable by using the PBRT method (2).

  • c ND, not determined.

  • d References correspond to previously partially characterized strains that have been fully studied here.