Table 2.

Antimicrobial peptide resistance of a P. aeruginosa PAK ΔpmrAB phoQ6 mutant

CAPPAK ΔpmrAB phoQ+ LD50a (mg/liter)PAK ΔpmrAB phoQ6
LD50 (mg/liter)Fold increase in Pm resistance
PMB<0.58>16
Protegrin-10.50.51.0
C18G351.7
  • a LD50, 50% lethal dose.