TABLE 1.

In vitro inhibitory concentrations of antiherpetic drugs in different cell culture systems and assays

VirusIC50 value or range (μg/ml); reference
AcyclovirPenciclovirFoscarnetCidofovirAdefovir
HSV-10.02-0.9; 380.04-1.8; 3824-60; 383.5-8.9; 1777; 154
HSV-20.03-2.2; 380.06-4.4; 3824-60; 383.5-8.9; 1777; 154
VZV0.8-4.0; 381.6-8.0; 3824-60; 380.22; 17710; 154
HCMV>20; 3851; 3830-90; 380.1-0.8; 17725; 154
EBV1.6-2.8; 81.5-3.1; 80.6-1.0; 690.008; 1770.3; 154