TABLE 2.

Inhibition of biofilm production by S. aureus clinical strains and S. epidermidis by PGGa

StrainGrowth (A578)Biofilm (A595)
0 μM12.5 μM0 μM12.5 μM
Staphylococcusspp.
    S. aureus SA113b0.68 ± 0.020.65 ± 0.036.31 ± 0.340.26 ± 0.28
    S. carnosus TM300c0.69 ± 0.020.70 ± 0.010.12 ± 0.010.10 ± 0.01
    S. epidermidis ATCC 355470.50 ± 0.010.42 ± 0.011.42 ± 0.090.15 ± 0.11
    S. epidermidis RP62A0.57 ± 0.090.56 ± 0.096.43 ± 0.044.18 ± 0.54
MSSA
    SA130.69 ± 0.090.67 ± 0.060.98 ± 0.130.12 ± 0.04
    SA330.79 ± 0.010.79 ± 0.040.80 ± 0.070.13 ± 0.03
    SA410.65 ± 0.020.61 ± 0.051.67 ± 0.270.36 ± 0.05
    SA2850.56 ± 0.090.46 ± 0.030.86 ± 0.090.16 ± 0.02
    SA2880.55 ± 0.010.50 ± 0.010.83 ± 0.020.10 ± 0.01
    SA2890.77 ± 0.020.72 ± 0.071.16 ± 0.010.35 ± 0.01
MRSA
    SA440.66 ± 0.080.64 ± 0.041.33 ± 0.010.46 ± 0.01
    SA1300.61 ± 0.120.62 ± 0.173.05 ± 0.100.32 ± 0.04
    SA4350.64 ± 0.100.67 ± 0.090.97 ± 0.090.46 ± 0.06
    SA4860.76 ± 0.080.65 ± 0.021.94 ± 0.190.26 ± 0.07
    SA7030.74 ± 0.100.70 ± 0.072.33 ± 0.020.88 ± 0.07
    SAChu0.56 ± 0.020.52 ± 0.048.06 ± 0.100.77 ± 0.11
  • a Values are the mean inhibition at the indicated PGG concentration ± SD.

  • b S. aureus SA113 is a biofilm-producing strain used as a positive control.

  • c S. carnosus TM300 cannot form biofilm and was thus used as a negative control.