Table 6.

Intracellular diamidine concentration after 1 h of exposure to 10 μM permeant

Cell lineSource conditionDiamidine concn (μM ± SEM)
DB75DB820CPD0801
s427Ex vivo596 ± 203264 ± 2264.0 ± 13
In vitro12.6 ± 2.20.43 ± 0.120.15 ± 0.03
tbat1−/−Ex vivo21.3 ± 1.75.70 ± 0.221.12 ± 0.42
In vitro12.2 ± 4.00.24 ± 0.050.15 ± 0.03