Table 3.

Number of B. cenocepacia LMG 16656 CFU in the lungs of mice after treatment with TOB alone or in combination with BHa

Treatment (mg/kg)No. of miceCFU/g of lung (avg ± SEM)Reduction in bacterial load (%) compared to untreated control mice
TOBBH
001856,752 ± 13,003
1001429,233 ± 3,75347.5
1021126,793 ± 3,56152.1
20076,267 ± 1,81388.8
20248,128 ± 4,60985.9
300104,560 ± 1,71491.9
3027559 ± 119*99.0*
  • a *, Significantly different compared to treatment with antibiotic alone (P < 0.05).