Table 2.

Substitutions in penicillin binding protein 1 of H. pylori strains

Strain or group (na)AMX MIC (μg/ml)Substitution at penicillin binding protein 1 position:
374406414535593599601
KS04614AspGlyGly
KS04780.5Asp
KS04870.5LeuArg
KS04390.25AlaAla
KS04760.25AspGly
KS04700.25Asp
KS04440.12AlaAla
KS0464, KS04790.12Asp
KS04930.12Pro
KS04340.06Ala
KS0466, KS04910.06Asp
KS05030.06Arg
KS05020.06
AMX-susceptible strains (15)≤0.03ValGluSerAsn/AspbThrAlaVal
  • a n, no. of strains.

  • b 535Asn → Asp was detected in the amoxicillin-susceptible strains KS0447, KS0452, and KS0467.