Table 3.

Six-year trends in linezolid resistance rates observed in the LEADER Program (2004 to 2009; 33,378 isolates)

Organism (no. tested)% of isolates nonsusceptible or resistant to linezolida
200420052006200720082009
S. aureus (18,537)0.000.030.030.060.100.15
CoNS (4,526)0.201.131.611.761.641.47
Enterococci (4,577)0.800.641.831.130.550.49
S. pneumoniae (3,292)0.000.000.000.000.000.00
viridans group streptococci (925)NTNT0.000.000.000.00
Beta-hemolytic streptococci (1,521)NTNT0.000.000.000.00
All organisms (33,378)0.140.240.450.440.360.34
  • a CLSI interpretation criteria from M100-S20-U (2010). NT, not tested.