Table 5.

Polymyxin B susceptibility and lipid A profile lane in mutant R2 and complemented A. baumannii strains

Inserted mutationComplementing genePolymyxin B MIC (μg/ml)Lipid A profile (lane in Fig. 1)
None (mutant R2)None82
pmrB::KmNone0.53
pmrB::KmpWH1266 (empty vector)0.5
pmrB::KmpmrABWT0.25
pmrB::KmpmrABR244
pmrB::KmpmrABR545