Table 2

MICs for Y105 SHV variants

StrainModal MIC (mg/liter)a
AMPAMP50/CLAVAMP50/SULAMP50/TAZOCROCAZCF
DH10B4No growthNo growthNo growth0.250.51
SHV-1>16,3842256>320.53264
Y105A1281280.50.52
Y105C12814160.50.516
Y105D1,024832>320.50.58
Y105E1,0241664>320.50.58
Y105F16,384464>321232
Y105G51224320.50.516
Y105H2561440.50.54
Y105I1,02424320.50.516
Y105K51222160.250.58
Y105L32No growthNo growthNo growth0.50.58
Y105M2,048832320.50.532
Y105N512216160.50.532
Y105P4,096816320.50.532
Y105Q2561480.50.532
Y105R1,0244161620.532
Y105S2,048832>320.50.516
Y105T1,024216>320.50.516
Y105V512116320.50.532
Y105W8,192164>320.5232
  • a Values are averages of 3 to 6 determinations. AMP, ampicillin; AMP50, ampicillin fixed at 50 mg/liter; AMP50/CLAV, ampicillin fixed at 50 mg/liter with various clavulanic acid amounts; AMP50/SUL, ampicillin fixed at 50 mg/liter with various sulbactam amounts; AMP50/TAZO, ampicillin fixed at 50 mg/liter with various tazobactam amounts; CRO, ceftriaxone; CAZ, ceftazidime; CF, cephalothin.