Table 2

Predictors of quinolone versus trimethoprim-sulfamethoxazole (TMP-SMX) choice among patients prescribed an antibiotic for urinary tract infectiona

CharacteristicResult (no. [%]) for:OR (95% CI)Adjusted OR (95% CI)
TMP-SMX (n = 2,537)Quinolone (n = 9,262)
Indication
    Cystitis2,449 (96.53)8,225 (88.80)ReferentReferent
    Pyelonephritis88 (3.47)1,037 (11.20)3.51 (2.67–4.61)3.71 (2.76–4.98)
Age, yr
    ≥17 to <651,452 (57.23)5,228 (56.45)Referent
    ≥651,085 (42.77)4,034 (43.55)1.03 (0.84–1.28)
Sex
    Male366 (14.43)1,810 (19.54)ReferentReferent
    Female2,171 (85.57)7,452 (80.46)0.69 (0.54–0.89)0.71 (0.55–0.90)
Region
    German2,142 (84.43)7,269 (78.48)Referent
    Latin395 (15.57)1,993 (21.52)1.49 (0.93–2.37)
Attitude of patient
    Neutral2,104 (82.93)8,053 (86.95)Referent
    Favoring433 (17.07)1,209 (13.05)0.73 (0.46–1.16)
Yr
    2006797 (31.42)2,888 (31.18)Referent
    2007780 (30.74)3,221(34.78)1.14 (0.95–1.37)
    2008960 (37.84)3,153 (34.04)0.91 (0.73–1.12)
Physician specialty
    General practitioner1,937 (76.35)6,414 (69.25)Referent
    Internal medicine600 (23.65)2,848 (30.75)1.43 (0.88–2.32)
Prescribing rateb
    Low1,763 (69.49)5,272 (56.92)ReferentReferent
    High669 (26.37)3,474 (37.51)1.74 (1.10–2.74)1.75 (1.10–2.77)
  • a Abbreviations: CI, confidence interval; OR, odds ratio; TMP-SMX, trimethoprim-sulfamethoxazole.

  • b Total number of prescriptions analyzed for prescribing rate is 11,178. Categories are based on frequency of antibiotic treatment by physician among patients presenting with influenza-like illness.