Table 1

Characteristics of Campylobacter strains used in this study

StrainaDescriptionEry MIC (μg/ml)bMutation in 23S rRNAc
Erys strains
    ATCC 700819Highly motile variant of C. jejuni NCTC 111682None
    Bd34-2*Erys isolate from a chicken inoculated with 700819 and treated with tylosin-containing feed2None
    Bd41-3*Erys isolate from a chicken inoculated with 700819 and treated with tylosin-containing feed2None
Clonally related Eryr strains
    J.L.270*Eryr isolate from a chicken inoculated with 700819 and treated with tylosin-containing feed32None
    J.L.272*Eryr isolate from a chicken inoculated with 700819 and treated with tylosin-containing feed>512A2074G
    J.L.273*Eryr isolate from a chicken inoculated with 700819 and treated with tylosin-containing feed>512A2074G
Isogenic Eryr strains
    T.L.101Laboratory-constructed Eryr transformant from 700819>512A2074G
    T.L.102Laboratory-constructed Eryr transformant from 700819>512A2075G
    T.L.103Laboratory-constructed Eryr transformant from 700819>512A2075G
  • a *, Clonally related to 700819 and the dose of tylosin in the feed was 50 mg/kg of feed (34); †, transformants were from three independent transformation experiments.

  • b Determined by the agar dilution method.

  • c Corresponding to the nucleotide positions in the 23S rRNA gene of C. jejuni NCTC 11168.