Table 1

Demographics and covariates of patients included in the rifampin pharmacokinetic-enzyme turnover modela

ParameterValue for patients from:
South AfricaSenegalBeninGuinea
Total no. of patients101271927
No. of male patients59221221
No. of female patients42576
No. of HIV+ patients49023
Median FFM (interquartile range)44 (37–49)48 (42–50)45 (39–47)46 (43–50)
Median body wt (kg) (interquartile range)56 (50–61)55 (52–61)53 (50–58)56 (51–60)
Median age (yr) (interquartile range)28 (24–37)26 (23–32)25 (23–31)34 (25–44)
Median CLCR (ml · min−1) (interquartile range)98 (85–115)91 (81–106)95 (81–124)75 (67–88)
  • a Continuous covariates are given as medians (interquartile ranges). FFM, fat-free mass; CLCR, creatinine clearance.