Table 1

Inhibition of E. coli-coupled in vitro transcription/translation in the presence and absence of Tet(M)

AntibioticIC50 (μg/ml) ±SD
With Tet(M)Without Tet(M)
TP-4340.29 ± 0.090.27 ± 0.16
Tigecycline0.08 ± 0.010.09 ± 0.04
Tetracycline1.26 ± 0.486.50 ± 3.30
Linezolid1.30 ± 0.281.08 ± 0.74