Table 2

MIC/MEC value comparison for clinical versus environmental isolates of P. apiosperma and P. boydii for all tested antifungal compounds (AMB, CAS, ITC, ISA, VRC, ANI, POS, and MICA)

SpeciesnaMIC and MEC (μg/ml)b and GM values
AMBCASANIMICAITCVRCPOSISA
RangeMIC50MIC90GMRangeMEC50MEC90GMRangeMEC50MEC90GMRangeMEC50MEC90GMRangeMIC50MIC90GMRangeMIC50MIC90GMRangeMIC50MIC90GMRangeMIC50MIC90GM
P. apiosperma124*0.5–>168>166.50.5–>8181.60.125–>80.580.90.006–>80.1254**0.20.25–>16>16>1615.30.25–>8120.90.25–>161>16**2.01–>168167.1
291–>1616>169.01–>8121.20.125–80.540.60.031–>0.50.1250.5**0.10.5–>16>16>1620.30.25–4121.00.25–>162>16**5.11.00–>168169.0
P. boydii44*0.5–>1616>1611.31–>8282.10.25–>8141.30.062–>80.2580.40.125–>16>16>1611.80.125–20.520.70.125–>161>161.50.50–>168165.8
142–>1616>1613.11–>82>83.10.5–>8281.80.062–>80.25>81.24.0–>16>16>1627.60.5–1110.80.5–2121.12–16885.9
  • a *, The number of isolates obtained from clinicalspecimens; †, the number of isolates obtained from environmental samples.

  • b **, GM MIC/MEC exhibiting a statistically significant difference between clinical and environmental isolates (P ≤ 0.05).