Table 3

VIM mutation profiles

NameMutation profile
VIM-1F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, V148A, S215N, I223V, Y224H, R228S, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-2
VIM-3Q59K, N150aS
VIM-4F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, V148A, S215N, I223V, Y224H, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-5F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, A130K, V148A, S215N, I223V, Y224L, E225A, I248V, Q253K, Q257E, F258V, K301Q, T304A, K308T, T311K, V316A
VIM-6Q59R, N150aS
VIM-7K2Q, L3I, L4R, K6-, L7F, Y10G, L11I, T12S, S14F, I15V, I18V, A19L, S20G, P21S, L22A, F24Y, V26A, D27Q, S28P, S29G, S36D, E37D, Q47K, A49G, S60K, F61L, D62G, G63D, A65T, P68S, G77A, A93V, A112S, V113I, A138T, S141L, R144Q, V148A, E149A, I163V, T165A, E169K, G170A, A177V, L185V, T198G, S207A, A208V, S215R, Y218F, I223V, Y224H, L226A, T229E, D238N, T246A, S247T, E249K, H254R, Q257E, F258V, D298E, K301Q, A309T, T311K, N312V, S314P, V316A
VIM-8T142A
VIM-9T142I
VIM-10F258Y
VIM-11N150aS
VIM-12F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, V148A, S215N, I223V, Y224H, R228S
VIM-13F1L, L3V, L4I, K6S, V9F, L11M, I15L, I18V, F24H, V26G, D27E, S29R, A49D, Q59H, S60T, A65V, A89T, A93V, A112S, V127A, V148A, I163V, S215N, I223V, Y224L, T246G, I248V, Q257E, F258V, K301Q, T304A, V316A
VIM-14F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, G30S, S36N, V148A, S215N, I223V, Y224H, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-15Y218F
VIM-16S54L
VIM-17I15M
VIM-18Q59R, E147−, V148−, E149−, G150−
VIM-19F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, V148A, S215K, I223V, Y224H, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-23R228S
VIM-24R228L
VIM-25F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, A130K, V148A, S215N, I223V, Y224L, E225A, I248V, Q253K
VIM-26F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, V148A, S215N, I223V, Y224L, R228S, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-27F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, A57S, V148A, S215N, I223V, Y224H, R228S, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-28F1L, L3V, L4I, K6S, L11M, I15V, I18V, F24H, V26G, D27E, S28P, S36N, V148A, S215N, I223V, Y224L, I248V, Q253K, Q257E, F258V, K301Q, T304A, T311K, V316A
VIM-30S36N