Table 1

Fungal strains used in this study

StrainGenotypeCommentSource or Reference
Candida albicans
    SC5314Wild type18
    CAI4ura3Δ::imm434/ura3Δ::imm43416a
    AFA59bura3Δ::imm434/ura3Δ::imm434 RPS10::pAFC89bCAI4 carrying extra copy of CaERG11 under ACT1 promoterThis study
    AFA60aura3Δ::imm434/ura3Δ::imm434 RPS10::CIp10CAI4 transformed with URA3 vectorThis study
    AFA63aura3Δ::imm434/ura3Δ::imm434 RPS10::pAFC92aCAI4 carrying extra copy of CaERG11 under PCK1 promoterThis study
    AFA21ura3Δ::imm434/ura3Δ::imm434 RPS10::pPCK1-GFPCAI4 transformed with URA3-PCK1 vectorThis study
    FH5Clinical isolate, highly resistant to fluconazole34, 57
    DSY2091ura3Δ::imm434/ura3Δ::imm434 cna1Δ::hisG-URA3-hisG/cna1Δ::hisGcna1Δ/cna1Δ mutant55
    DSY2115ura3Δ::imm434/ura3Δ::imm434 cna1Δ::hisG/cna1Δ::hisG LEU2::CNA1::URA3CNA1 reintegrant55
    DSY2146ura3Δ::imm434/ura3Δ::imm434 cna1Δ::hisG/cna1Δ::hisG LEU2::CNA1tr::URA3CNA1tr reintegrant55
Saccharomyces cerevisiae BY4742MATα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0Reference strainEuroscarf