Table 4

Univariate analysis of the effect of glucocorticoid coadministration on voriconazole concentration

Concomitant medicationVoriconazole concn (mg/liter)a when parameter was:P valueb
PresentAbsent
Prednisone or prednisolone1.25 (2.2)1.60 (3.1)<0.01
Methylprednisolone1.00 (1.5)1.50 (2.8)<0.01
Dexamethasone0.40 (1.2)1.50 (2.8)<0.01
  • a Median (interquartile range).

  • b Mann-Whitney U test.