Table 2

FKS mutations and corresponding echinocandin MICs

IsolateMutationMIC (μg/ml) of drug
FKS1FKS2CaspofunginAnidulafunginMicafungin
Hot spot 1Hot spot 2Hot spot 1Hot spot 2
309D632HNoneNoneNone20.50.5
1D632YNoneNoneNone20.50.5
102NoneNoneF659delNone810.5
190NoneNoneF659delNone80.50.12
35NoneNoneF659LNone10.120.06
129NoneNoneF659LNone10.120.03
187NoneNoneF659LNone20.060.03