Table 4

Virulence genotypes, plasmid addiction systems, and plasmid replicon typesb

CharacteristicNo. (%) of isolates (unless indicated otherwise)P valuea
ST131-O25b (n = 41)ST131-O16 (n = 26)ST405 (n = 41)OST (n = 41)OverallOST vs:
ST131-O25bST131-O16ST405
Virulence genotype
    ExPEC status31 (76)6 (23)22 (54)19 (46)<0.0010.0120.0720.659
    Virulence score6 (5–6)5 (5–6)6 (6–8)4 (3–6)<0.0010.0020.193<0.001
No. of plasmid addiction systems4 (3–4)3 (2–4)3 (2–4)3 (2–4)0.4800.3050.7770.806
    vagCD8 (20)5 (19)2 (5)15 (37)0.0040.1390.1740.001
    relBE10 (24)7 (27)0 (0)1 (2)<0.0010.0070.0041.000
    ccdAB41 (100)21 (81)26 (63)26 (63)<0.001<0.0010.1741.000
    srnBC28 (68)16 (62)31 (76)27 (66)0.6241.0000.7960.467
    pemKI35 (85)16 (62)34 (83)21 (51)0.0010.0020.4580.004
    hok-sok12 (29)8 (31)29 (71)18 (44)0.0010.2520.3150.025
    pndAC7 (17)7 (27)6 (15)15 (37)0.0880.0800.4390.041
    parDE0 (0)0 (0)0 (0)0 (0)1.0001.0001.0001.000
Replicon type
    IncF41 (100)24 (92)41 (100)35 (85)0.0030.0260.4690.026
        IncFII40 (98)23 (88)39 (95)32 (78)0.0190.0140.3430.048
        IncFIA38 (93)16 (62)21 (51)17 (41)<0.001<0.0010.1360.507
        IncFIB30 (73)23 (88)32 (78)35 (85)0.4000.2761.0000.569
    ColE18 (44)2 (8)5 (12)18 (44)<0.0011.0000.0020.003
    IncI16 (15)2 (8)7 (17)11 (27)0.2470.2760.0640.424
    IncB/O5 (12)1 (4)9 (22)7 (17)0.2050.7560.1380.781
    IncU9 (22)4 (15)1 (2)7 (17)0.0400.7811.0000.057
    IncN3 (7)1 (4)0 (0)1 (2)0.4220.6161.0001.000
    IncP0 (0)0 (0)0 (0)3 (7)0.0640.2410.2770.241
    IncA/C1 (2)0 (0)0 (0)0 (0)1.0001.0001.0001.000
    IncL/M0 (0)0 (0)0 (0)1 (2)1.0001.0001.0001.000
    Nontypeable0 (0)2 (8)0 (0)3 (7)0.0500.2411.0000.241
  • a Comparison between the ST131-O25b and ST405 groups revealed that statistical differences were found only in carriage of relBE (P = 0.013), FIA (P < 0.001), ColE (P = 0.003), and IncU (P = 0.014).

  • b OST, other sequence types; ExPEC, extraintestinal pathogenic E. coli. Continuous variables are presented as medians (interquartile ranges).