Table 5

Activity of eravacycline against S. aureus strains expressing NorA or MepA efflux pumps

CompoundMIC (μg/ml)
SA981 (parent)SA982 (norA)SA983 (parent)SA984 (mepA)
Eravacycline0.0040.0040.0040.016
Tigecycline0.0630.130.0161
Tetracycline0.50.50.50.5
Ciprofloxacin0.51624
Meropenem0.250.130.130.13