Table 8

Single-step resistance frequency for P. aeruginosa ATCC 27853

AntibioticMIC (μg/ml)Concn selected (MIC multiple)Resistance frequency
AN336544-fold1.2 × 10−7
10-fold4.8 × 10−8
Ceftazidime24-fold2.9 × 10−7
10-fold2.6 × 10−7
Ciprofloxacin0.254-fold2.0 × 10−7
10-fold<2.8 × 10−9
Tobramycin0.54-fold5.5 × 10−7
10-fold8.3 × 10−9