Table 1

Ceftolozane MICs alone and in combination with tazobactam

OrganismCeftolozane MIC (mg/liter)Ceftolozane MIC (mg/liter) + tazobactamESBL(s)
2:14:18:148
E. coli ATCC 259220.5None
E. coli NIH-J0.06None
K. pneumoniae ATCC 438161.4None
K. pneumoniae 2161None
P. aeruginosa ATCC 278530.5None
P. aeruginosa 4304A0.7None
P. aeruginosa PO20.5None
P. aeruginosa 3131None
E. coli 604222.424821TEM 10
K. pneumoniae 4105>6411.21622.41611.2TEM 26, SHV-1
K. pneumoniae 4110>645.611.23284TEM 10, SHV-1
K. pneumoniae 81-1260A44.824821CTX-M3, AmpC
E. cloacae 81-1291A11.221.4410.7SHV-5